| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_47054da942b228608c4fe1c2dbec1fdb
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1b5eaa25a963e90610ce9ad8d55c1656
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5207b2135384ecf97c3ffaa8db4cdac4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8507202fd88d32cfd6929e35df740e66
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_46f442bf71ad881826c4e3cb979ac1b8 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-093
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-10 |
| filingDate |
2005-06-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_efc1d6a89ee4ca951ce95d10668ed17e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_64b0838a361a3f0c756b40598ed1d6bc
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_445a872445040087d2097ce490f91c48
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_eb979b5480d246da32b177ef8f2c2684 |
| publicationDate |
2006-01-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2006004935-A2 |
| titleOfInvention |
Pegylated cardiolipin analogs, methods of synthesis, and uses thereof |
| abstract |
The invention provides synthetic methods for PEGylated cardiolipins with varying linkers. The methods can be employed to prepare PEGylated cardiolipin with different fatty acid and/or alkyl chain length with or without unsaturation. The PEGylated cardiolipin, prepared by the present methods, can be incorporated into liposomes that can also include active agents such as hydrophilic or hydrophobic drugs for the treatment of human and animal diseases. In addition, the PEGylated cardiolipin can be incorporated into liposomes that include compounds for therapeutic and diagnostic imaging. The use of such liposomes with PEGylated cardiolipin prolongs the period of liposomal circulation without disrupting the lipid bilayer. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2008073230-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1986607-A4
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2010512386-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103193976-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7824708-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1986607-A2 |
| priorityDate |
2004-06-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |