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classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-05
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filingDate 2005-06-16-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_905bdcd8ded54dc42678ad85dbfbdb7d
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publicationDate 2006-01-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-2006000603-A1
titleOfInvention Use of trans-resveratrol as a therapeutic agent for the treatment of male infertility and/or subfertility in mammals
abstract The invention relates to the use of trans-resveratrol as a therapeutic agent for the treatment of male infertility and/or subfertility in mammals. Trans-resveratrol induces an increase in sperm concentration owing to overall spermatogenic tissue growth. Trans-resveratrol also induces an increase in the seric concentration of follicle-stimulating hormone (FSH), luteinizing hormone and testosterone, which involves hypophyseal stimulation in the hypothalamic-hypophyseal-testicular axis. Unlike other medicaments available for male infertility treatment, trans-resveratrol is used for the treatment of male infertility and/or subfertility having different causes, such as idiopathic infertility, high levels of reactive oxygen species or inflammatory alterations. Given that male infertility and/or subfertility generally have multiple converging causes, trans-resveratrol is advantageous in that it has various different action mechanisms.
priorityDate 2004-06-18-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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