| abstract |
The invention relates to the novel ortho-substituted (3-hydroxyphenyl)-acetic acid benzylidene hydrazides of formula (I), wherein R<SUP>1 </SUP>to R<SUP>9</SUP> are defined as in claim 1. Said novel compounds are SGK inhibitors and can be used in the treatment of SGK-relates diseases and disorders such as diabetes, obesity, metabolic syndrome (dyslipidemia), systemic and pulmonary hypertension, cardiovascular diseases and renal diseases, and generally for any kind of fibroses and inflammatory processes. |