Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0c55eda15c54fcec84649db474c9348c http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3bf194612e66a0e282c600ce65a626c1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_dda9504b90515d6038a96a0061b49b23 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b20985e3f9c21d3e4f3d711b8332a9b0 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08G18-4833 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08G65-329 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08G18-714 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08G65-333 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08G65-329 |
filingDate |
2005-06-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_eecb90a184f4b62b1d8f97b8c2e31cb0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b8efc03bedab6421f74a39b4b6b1e4a3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_133c523b03ecce8b2cbd10394af4e958 |
publicationDate |
2005-12-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2005123139-A1 |
titleOfInvention |
Bifunctional derivatives of polyethylene glycol, their preparation and use |
abstract |
The patent describes homo- or hetero-bifunctional derivatives of polyethylene glycol (PEG) obtained by selectively modifying the hydroxyl end groups of commercial PEGs of different molecular weights with reactive bifunctional molecules. The synthesis process comprises steps involving sequential derivatization of PEG terminal hydroxyl groups with a bifunctional compound, purification of the bifunctional PEG obtained and/or protection of its functional groups with possible selective removal of terminal protections. The bifunctional PEGs (biPEG) obtained are usable as carriers and/or stabilizers for substances used for diagnostic, prophylactic and therapeutic purposes, conjugated to the same biocompatible biPEG support. The bifunctionalized PEG derivatives can also be used in supported synthesis processes. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11725073-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3077072-B1 |
priorityDate |
2004-06-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |