| abstract |
It is intended to provide an antibody which specifically recognizes the stereostructure of the extracellular domain of a polypeptide encoded by PERP (p53 apoptosis effector related to PMP-22) gene and binds to the extracellular domain. This antibody is useful in treating various diseases associated with the overexpression of the polypeptide encoded by PERP gene. Furthermore, this antibody makes it possible to specifically detect the polypeptide encoded by PERP gene or a cell expressing this polypeptide by an immunological procedure and, therefore, is useful in diagnosing various diseases in which PERP participates. |