| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1005ddc0af8ef9c5d7c3773fc8d109ce
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6ef9000ddde8ba7294b8119ff16c217d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_33b863e17a953e741f188564b69ddef6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_017687b1a30268594a417c8eec72ed19
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0bbef4f6fed6600c9dfa488b4f846726
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7b7bf986052a649328e53da1b530a0b1 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y302-01123
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P19-26
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-2402 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-24 |
| filingDate |
2005-06-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2d97691b355ea186bac6ad4339977e56
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a2a0d18c97a761e6a98c4a1b4cef4e1f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_738530954e9b8a119ac51369c2017cfb
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6220e72a66d3ef519945426fe82cb961 |
| publicationDate |
2005-12-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2005118798-A2 |
| titleOfInvention |
Mutant endoglycoceramidases with enhanced synthetic activity |
| abstract |
The present invention relates to a novel endoglycoceramidase whose hydrolytic activity has been substantially reduced or eliminated, such that the enzyme is useful for synthesis of glycolipids from a monosaccharide or oligosaccharide and a ceramide. More specifically, the endoglycoceramidase is a mutant version of a naturally occurring endoglycoceramidase, preferably comprising a mutation within the active site or the nucleophilic site of the enzyme and more preferably comprising a substitution mutation of the Glu residue within the active site or the nucleophilic site. Also disclosed are a method for generating the mutant endoglycoceramidase and a method for enzymatically synthesizing glycolipids using this mutant enzyme. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10555959-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112708687-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2023118378-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112708687-B |
| priorityDate |
2004-06-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |