| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a74cfbbb1b5705badb5d9dce5fff10d5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bd4c54ba5a7274187c661e75b26137b8 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-473
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-455
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-522
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-06 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-522
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-473
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-455 |
| filingDate |
2005-06-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a8e54cf2379ea11894211830b9fb435e |
| publicationDate |
2005-12-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2005117893-A2 |
| titleOfInvention |
Methods of treating cellular proliferative disease using naphthalimide and parp-1 inhibitors |
| abstract |
A method of treating a cellular proliferative disorder in a patient through the use of a naphthalimide and a PARP-1 inhibitor is disclosed. In one embodiment the naphthalimide is amonafide or an analog thereof. Fig. 9 depicts an increase in inhibition of cellular growth observed after treatment with amonafide in combination or sequentially with nicotinamide or caffeine in an in vitro cell viability assay. |
| priorityDate |
2004-06-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |