Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b85cbdbcc47630dffd2ba7ccf67dfcee http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1394e66eb648f9bf0a1f5507fe25b67b http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a186fb3ec97c01577f074464094d981c http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_aef2fd36408b19ed18681d00023d0cc6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0b617e9b1006ca66689ef8a2d900a3ff http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5887e24831e49a12d8958f84fd6445bd http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_692dc75829481c48c017b52f352e2bad http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9e1584db7fded0f7d90254081ecff57c |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1271 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4745 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-127 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4745 |
filingDate |
2005-05-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_48ce41d1ee6bc0654e13e4036358edcc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d28c942f1bdcc62c46c36f0024cf757b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_df9f006634944f6bb0c835c29edf0adb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_02b123a5386e9cb17fc126cff24181e0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_034a3565e7a09460889c4d222b94d85f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5b388534602390ac032a3b9c473b0ceb |
publicationDate |
2005-12-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2005117878-A1 |
titleOfInvention |
Irinotecan preparation |
abstract |
An irinotecan preparation having irinotecan and/or a salt thereof highly carried by a closed vesicle carrier, which exhibits a strikingly prolonged retention in blood as compared with that of conventional irinotecan liposome preparations and is capable of being present in blood for a prolonged period of time. There is provided an irinotecan preparation comprising closed vesicles formed of a lipid membrane wherein irinotecan and/or a salt thereof is sealed in a concentration of at least 0.07 mol/mol (medicine mol/total membrane lipid mol). The irinotecan preparation preferably has an ion gradient between an inner water phase and an outer water phase within the closed vesicles. The closed vesicles are preferably liposomes, and the liposomes preferably have only the external surface thereof modified with a surface modifier containing a hydrophilic polymer. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2010058840-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10022365-B2 |
priorityDate |
2004-06-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |