| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9c150ab009205a5e57f66f5ff38c0b81
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4c27b15a72ea683645313b572a604275
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9b447b90bcfaadd3c5764c762994c33b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fffa0c957276738d0db5973525e8046e |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-78 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-78
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 |
| filingDate |
2005-05-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1536ddc4571737b0ac11069fc6892b25
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d08dc0f8830a8bc812802c6edf6291df
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4d835fd15451f845f6c1ce908b618e97 |
| publicationDate |
2005-12-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2005116658-A2 |
| titleOfInvention |
Method for determining a tissue degradation process by detection of comp neoepitopes |
| abstract |
The present invention relates to a method for determining a tissue degradation process by detection on COMP (Cartilage Oligomeric Matrix Protein) neoepitopes, where said COMP neoepitopes appear after cleavage of COMP at one or more site between position 530 and 660 of the amino acid sequence of COMP. Such as between position 550 (N550) And 551 (W551) or between position 625 (N625) and 626 (P626). Furthermore, the invention relates to antibodies against COMP neoepitopes and to fragments and peptides containing COMP neoepitopes for generation of such antibodies, which fragments or peptides comprise in or more COMP neoepitopes with at least partial identity to a selected group of COMP peptides derived from the sequence between amino acids 539-550, 551-562, or 626-637 of human COMP. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9632097-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2015522817-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AU-2013281240-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2014003679-A1 |
| priorityDate |
2004-05-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |