| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_910e398b177a8d767e762b4554392fa0
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0d0446a5bd77c7da68216fc2e3f05d48
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_936f8f9d14531b67708d9db8fa45ca73 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-07 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-07 |
| filingDate |
2005-05-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bfe6c27f1b643d092b4fcd816ad18072
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ae5e42111d4c176eeca90d70606be028 |
| publicationDate |
2005-12-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2005115429-A1 |
| titleOfInvention |
Methods and kits for diagnosing and/or assessing severity and treating gaucher disease |
| abstract |
Methods and kits for treating Gaucher disease are provided. The methods are based on using agents capable of inhibiting proteasomal degradation of glucocerebrosidase and/or elevating a level of mis-folded yet active glucocerebrosidase in cell lysosomes. Also provided are methods and kits for diagnosing and/or assessing a severity and determining prognosis of Gaucher disease or other diseases associated with abnormally folded proteins which are retained in the ER. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2271213-A4
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2011022843-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106906280-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106906280-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2271213-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9901612-B2 |
| priorityDate |
2004-05-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |