| abstract |
[PROBLEMS] To provide a composition for inhibiting the onset of arteriosclerosis by using a rare sugar D-psicose and an inhibition method. [MEANS FOR SOLVING PROBLEMS] A composition for inhibiting the onset of arteriosclerosis characterized by comprising, as the active ingredient, D-psicose having antiatherogenic effects. The antiatherogenic effects as described above include an effect of inhibiting or lessening the expression of a chemokine or a cytokine relating to arteriosclerosis in vivo and an effect of promoting the expression of a receptor participating in the amelioration of arteriosclerosis without affecting the expression of an arteriosclerosis inducer. This composition is used in the form of a product selected from the group consisting of sweeteners, seasonings, food additives, food materials, foods, drinks, health foods and drinks, drugs, quasi drugs and feeds containing D-psicose and/or its derivative and/or a mixture thereof. A method of inhibiting the onset of arteriosclerosis by using the above composition. |