| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cac58681993553c815f0c93f78e33bfe
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_04420713d8ca0e51f499cd44298a4692
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_291956806675604a659d9089eee9807c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_90e1e850c84cb2ea0b02bdbb5cb4ccb4 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2018
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2013
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2027
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-137
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-194 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-194
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-137 |
| filingDate |
2005-05-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6952a1b1106cd99d29cef127e2f0cb10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_47ad26f78ae548f7e6aff34dbf9762c3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_22dcaabf68262f4a30bbb60088e42494 |
| publicationDate |
2005-11-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2005110373-A1 |
| titleOfInvention |
Rapidly soluble granulate of bromohexine or bromohexine hydrochloride, method for the production of said granulate and the use thereof |
| abstract |
The invention relates to a rapidly soluble granulate that is obtained by (a) the production of an aqueous granulation liquid containing at least one binding agent and (b) the spraying of the granulation liquid obtained in step (a) onto a fluidised bed in a countercurrent at a constant supply air temperature onto a support containing at least one carbohydrate, whereby bromohexine or bromohexine hydrochloride and citric acid are introduced, independently of one another into the granulation liquid and/or onto the support. The invention permits for the first time the provision of a water-soluble granulate containing bromohexine or bromohexine hydrochloride as the active ingredient. Said inventive granulate is water-soluble, despite the fact that the bromohexine or bromohexine hydrochloride is practically insoluble in water, i.e. the granulate dissolves completely in water within a few minutes and releases the active ingredient in its entirety. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102293741-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104287970-A |
| priorityDate |
2004-05-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |