| abstract |
The invention features compositions for treatment of pain or nociception and methods of their use. The compositions include the combination of two or more drugs, such as an opioid (e.g., delta, kappa, or mu), a non-steroidal anti-inflammatory drug (NSAID) or acetaminophen, and a dopaminergic agent. These drug combinations may be administered alone (i.e., treatment is accomplished using a composition that consists of or consists essentially of the drug combination itself), or the drug combinations may be administered in conjunction with yet additional compounds. |