| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8381805eba6d034fc77bd230dd02e6e2
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_36c0172f6059c0b200188dba42db7fa6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_042695e84b53e4529e1e9851e58cf6d6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5d177ed3c8ebd750e5105f038acad176
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5fee7b6510455e918afa7ef2ac513533 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2510-02 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P21-005 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-00 |
| filingDate |
2005-05-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_95fcaf6b2123e5aed9e4ecfad940e43e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_faed2e7d2e005351e7dcbd0f70d10148
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9a2fa5656a485dd5807fc802696b82cc |
| publicationDate |
2005-11-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2005105156-A1 |
| titleOfInvention |
Method for expressing sialylated glycoproteins in mammalian cells and cells thereof |
| abstract |
Methods and systems for producing glycoproteins having sialylated oligosaccharides are provided. The invention comprises the genetic engineered cells with a CMP-sialic acid transporter (CMP-SAT) gene so that the cells express the CMP-SAT protein or fragment thereof at an above endogenous levels. The increase in CMP-SAT expression allows for the increased transport of the CMP-sialic acid into the Golgi apparatus so as to obtain sialylation of glycoproteins at above endogenous levels. In particular, the methods and systems of the invention are useful for producing complex sialylated glycoproteins in mammalian cells of interest, for example Chinese Hamster Ovary (CHO) cells. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2019190752-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11224638-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11229686-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11186832-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11564978-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11224637-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11400140-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2015182792-A1 |
| priorityDate |
2004-05-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |