Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_00924da5ad2b0e91dcd35bab32529f78 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4577a5200186457fceddd6ad0fa48795 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f3b719e471d3c60a6effcec64bd9e3f3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9fb9fcb41f14c2754b13d2af7599052c http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7ffcaa6cf82f2965053939371fe30bfe http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_07c9542186133097bd6bbb7d92393090 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C401-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C401-00 |
filingDate |
2005-02-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ab0ec7b7924872fcc0ed6e62bd74c661 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_89f7b91b6e6c710a40953867cf91bb3e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_765caa6d4367394156cb6f980d0a71c5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9d047ccf3d2f3ba83cf9bef74ed501ee http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e09894dbc05f6c539f39f6bb08adf4e0 |
publicationDate |
2005-11-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2005102995-A1 |
titleOfInvention |
2-alkylidene-18,19-dinor-vitamin d compounds |
abstract |
2-alkylidene-18,19-dinor-vitamin D compounds are disclosed as well as pharmaceutical uses for these compounds and methods of synthesizing these compounds. These compounds are characterized by low bone calcium mobilization activity and high intestinal calcium transport activity. This results in novel therapeutic agents for the treatment and prophylaxis of diseases where bone formation is desired, particularly osteoporosis, as well as autoimmune diseases such as multiple sclerosis, diabetes mellitus and lupus. These compounds also exhibit pronounced activity in arresting the proliferation of undifferentiated cells and inducing their differentiation to the monocyte thus evidencing use as an anti-cancer agent and for the treatment of skin diseases such as psoriasis. These compounds also increase both breaking strength and crushing strength of bones evidencing use in conjunction with bone replacement surgery such as hip and knee replacements. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2009532457-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2009533483-A |
priorityDate |
2004-04-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |