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filingDate 2005-04-21-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2005-11-03-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-2005102291-A1
titleOfInvention Seamless capsule containing water-soluble active ingredient
abstract A seamless capsule which contains a water-soluble active ingredient and in which the water-soluble active ingredient is prevented from becoming instable; and a process for producing the capsule. The seamless capsule comprises: contents comprising a water-soluble active ingredient and an oily substance; a film with which the contents are covered; and an interlayer which is disposed between the contents and the film and comprises an oily substance in which the water-soluble active ingredient is insoluble or immiscible and which is insoluble in or immiscible with water, has a melting point in the range of 10-65°C, and does not dissolve in or mix with the contents at any temperature not higher than the melting point during the capsule production. The process, which is for producing a seamless capsule containing a water-soluble active ingredient, employs an apparatus for seamless-capsule production which has a multiannular nozzle having three or more annular orifices with diameters increasing in order.
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