| abstract |
The invention provides a human ADRA1D which is associated with the gastrointestinal and liver diseases, cardiovascular disorders, metabolic diseases, inflammatory diseases, neurological disorders, urological disorders, respiratory diseases and cancer disorders. The invention also provides assays for the identification of compounds useful in the treatment or prevention of gastrointestinal and liver diseases, cardiovascular disorders, metabolic diseases, inflammatory diseases, neurological disorders, urological disorders, respiratory diseases and cancer disorders. The invention also features compounds which bind to and/or activate or inhibit the activity of ADRA1D as well as pharmaceutical compositions comprising such compounds. |