| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0b386f154b92a5bc936dc9e968987a2f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_33dafb5bbc2ec47ebcb7becbbe60f704
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7a271aaf257bc92661f2a21b54e24da8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a2f1f7e88be4eb805470399b2df3f875
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_dc9ee22e7be37ef31daa6ea7c1dae0ed |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J9-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J5-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J5-00 |
| filingDate |
2005-03-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2bd6032f331d3ed5ed724658adb8c5bb
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0aa01321c91a93e889e8c02d613bc3d9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6833bdf525244ef7aaf682a2df9304bc
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ceb5fddf9f8e87728e831a4cc7bd5f8a |
| publicationDate |
2005-10-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2005095431-A1 |
| titleOfInvention |
METHOD FOR PRODUCING 5α-PREGNANE DERIVATIVE |
| abstract |
Disclosed is a method for producing a mixture of 5α-pregnane derivatives represented by the general formulae (II) and (III) below which is characterized by reacting a pregnane derivative represented by the general formula (I) below with a metal selected from alkali metals and alkaline earth metals in the presence of a proton donor, an amine and/or ammonia. By this method, a 5α-pregnane derivative which is useful as a synthetic intermediate for a squalamine can be produced from an easily-available raw material at high yield. (In the formulae, R1 represents a protecting group of a hydroxyl group, and R2, R11 and R12 independently represent a hydrogen atom or a protecting group of a hydroxyl group.) |
| priorityDate |
2004-03-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |