| abstract |
An object of the present invention is to search for a substance having an ability to form a vascular network. The present invention provides a novel vascular network forming agent comprising such a substance as an effective ingredient, which can be used in clinical applications, such as therapy for humans, and the like. A composition is provided for forming a network of blood vessels, comprising a peptide having an amino acid sequence X1-X2-X3-X4-X5-X6-X7 (SEQ ID NO. : 14), where X1 is serine (S), threonine (T),or a variant thereof, or is absent , X2 is valine (V), alanine (A), glycine (G), leucine (L), isoleucine (I), or a variant thereof, X3 is valine (V), alanine (A), glycine (G), leucine (L), isoleucine (I), or a variant thereof, X4 is an amino acid having an aromatic ring as a side chain or a variant thereof, X5 is glycine (G) or a variant thereof, X6 is leucine (L), alanine (A), glycine (G), valine (V), isoleucine (I), or a variant thereof, X7 is arginine (R ), lysine (K), or a variant thereof, or is absent; or a variant or salt thereof. |