http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2005094485-A3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_275823458990b94f78f4f2b96de34b86 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-136 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6886 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-0093 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
| filingDate | 2005-03-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ece940e1854c1ff06af7cf2cb63adea9 |
| publicationDate | 2007-03-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-2005094485-A3 |
| titleOfInvention | Drug screening |
| abstract | An isolated polypeptide containing (i) an immunogenic fragment of an RNR subunit (SEQ ID NO: 1 or 15) spanning Y162 or Y369 of SEQ ID NO: 1, or Y124 or Y331 of SEQ ID NO: 15, or (ii) a mutant fragment of SEQ ID NO: 1 or 15 in which at least one of the aforementioned Y residues is replaced by a non-tyrosine residue. Disclosed are related nucleic acids, expression vectors, host cells, reconstituted RNR enzymes, preparation methods, and compound screening methods. Also disclosed are RNAi agents for inhibiting expression of a gene encoding SEQ ID NO: 1 or 15. Within the scope of this invention are methods of treating a cell proliferation-associated disorder. |
| priorityDate | 2004-03-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
| Predicate | Subject |
|---|---|
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5651972-A |
| isDiscussedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID458397536 |
Total number of triples: 19.