Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9017ebfb67b994e996fb8269b48a3635 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5ec11172981122c7cc95dff341b28ea3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b5d89381dd37e76339ba062df2f90834 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_447c6842076d32048543e84c6c228a39 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3ae05f2b65b36c65d0914c528a69f737 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b3b600add25d3332de7d20386f1c44ba http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2355d8f43da51e768a2771b6fb653668 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-156 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6883 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
filingDate |
2005-03-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f385ddf5c508942ba5a434d976929432 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6c2e7b204e5934d4a3f9bef9f3c33acd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9b34d6fa16a9b4710769d22ebd142309 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6078146094b137324e3f6897f9e96c88 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bd6ec3991600dfc1d34a150cd93f74f2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4b3b4f8fc979aa9c8feff9bb786961bc |
publicationDate |
2005-10-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2005093096-A1 |
titleOfInvention |
Method and kit for detecting the risk of developing hypertension |
abstract |
The invention relates to a method for the prognosis or diagnosis of essential hypertension in humans. The inventive method comprises the detection of the presence or absence of a polymorphism in the KCNMB1 gene in a sample taken from the subject, said polymorphism causing an aminoacidic substitution of E (glutamic acid) for K (lysine) at position 65 of the corresponding encoded polypeptide. In particular, said polymorphism involves a substitution of a single nucleotide of G at position 352 of the sequence of the KCNMB1 gene for A. The invention also relates to methods, compounds and kits for the diagnosis and prognosis of essential hypertension in humans. The invention further relates to compounds for the prophylactic or curative treatment of essential hypertension. |
priorityDate |
2004-03-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |