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filingDate 2005-03-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f385ddf5c508942ba5a434d976929432
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publicationDate 2005-10-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-2005093096-A1
titleOfInvention Method and kit for detecting the risk of developing hypertension
abstract The invention relates to a method for the prognosis or diagnosis of essential hypertension in humans. The inventive method comprises the detection of the presence or absence of a polymorphism in the KCNMB1 gene in a sample taken from the subject, said polymorphism causing an aminoacidic substitution of E (glutamic acid) for K (lysine) at position 65 of the corresponding encoded polypeptide. In particular, said polymorphism involves a substitution of a single nucleotide of G at position 352 of the sequence of the KCNMB1 gene for A. The invention also relates to methods, compounds and kits for the diagnosis and prognosis of essential hypertension in humans. The invention further relates to compounds for the prophylactic or curative treatment of essential hypertension.
priorityDate 2004-03-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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