| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0a9e6421e9257148abad101e1ce6c162
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b72133d93dbbbc12e9999698687f614d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f64bd78a4cfee29a0cf1c33e8d72a517
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_82df356b9c2eca58b9cd0f424794afaf
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_825e4c1ce464ea1e02166f029ac57aef |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K5-06113
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K5-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H15-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H11-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K9-003
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H15-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H15-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-02 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K9-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H15-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-072
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H11-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H15-04 |
| filingDate |
2005-03-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_19a5eb5ad2dd5cf2ea8e854f6c0f9279
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6498c847e9d368a2cc12b14c66f7ec9f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1e2f583604131e6e86550c32e7896f9b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_21b0e1fe21713a320e52fe1c919213f4 |
| publicationDate |
2005-09-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2005090382-A1 |
| titleOfInvention |
Antithrombotic compound |
| abstract |
The present invention relates compounds of the formula (A) oligosaccharide-spacer-GpIIb/IIIa antagonist (A), wherein the oligosaccharide is a negatively charged oligosaccharide residue comprising four to twenty five monosaccharide units, the charge being compensated by positively charged counterions, and wherein the oligosaccharide residue is derived from an oligosaccharide which has (AT-III mediated) anti-Xa activity per se; the spacer is a bond or an essentially pharmacologically inactive linking residue; the GpIIb/IIIa antagonist is a residue mimicking the RGD and/or K(QA)GD fragment of fibrinogen, typically comprising an optionally esterified carboxylate moiety and a basic moiety located within the residue at a distance of 10-20 Å from each other; or a pharmaceutically acceptable salt thereof or a prodrug or a solvate thereof. The compounds of the invention have antithrombotic activity and can be used in treating or preventing thrombotic diseases. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1761510-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2009511543-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AU-2005256424-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9925174-B2 |
| priorityDate |
2004-03-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |