| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a0c50957122b975ddc1c0d61fb419847
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_be2931c6af5e9210e3271f92b718bd7b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2621d755a93c65093357a1c4c18ed034
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8123988eb4e39ea377620cd8d5e5630a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ebb6a553affdc364c91cffe3baf12564 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D211-90
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-455 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D211-90 |
| filingDate |
2005-03-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6e543af981fc992eccab3a97b3a747dc
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5ce1057df8855cc22bafb5dcfc112ed9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7c39fec94aa958a199eb723d9fb99151
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_21ce335b0cd69597ab6edd615c92a0ea |
| publicationDate |
2005-09-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2005089353-A2 |
| titleOfInvention |
(s)-amlodipine malate |
| abstract |
One aspect of the present invention relates to optically pur (S)-amlodipine malate. Another aspect of the present invention relates to (rac)-amlopidine malate. In a preferred embodiment, compound is optically pure (S)-amlodipine L-malate. Another aspect of the present invention relates to a pharmaceutical composition comprising optically pure (S)-amlodipine malate. Another aspect of the present invention relates to a method of preparing optically pure (S)-amlodipine malate, comprising admixing optically pure (S)-amlodipine with malic acid. Another aspect of the present invention relates to the various polymorphic and solvated forms of optically pure (S)-amlodipine malate. In another prefered embodiment the invention relates to polymorphic and solvated forms A-G. The present invention also relates to a method of preparing optically pure (S)-amlodipine malate, comprising combining a salt of optically pure (S)-amlodipine with a malate salt to give optically pure (S)-amlodipine malate. In a preferred embodiment, the malate salt is an optically pure L-malate salt. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2077994-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2077994-A4
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103044314-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11098015-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11091439-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11091440-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8362263-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2022508791-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9809549-B2 |
| priorityDate |
2004-03-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |