| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5ace8ba018de533dea74227c07570e4d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_da47af89c7586d5ca312cc69ffdcd664
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a2aa985f98db805627c4b48c0f23aa48
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_695ba0e419dc21ef88eafaeffa1f14ae |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-705
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2400-40 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D417-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-68 |
| filingDate |
2005-03-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4402d53e347ac0d90d5cc6e29b6e4a24
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7b47d4b21404a2e11cb173b5f71473b7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_365748b1aa144e658a302f0b21b5fdef |
| publicationDate |
2005-09-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2005089067-A2 |
| titleOfInvention |
Screening of anti-viral drugs and pharmaceutical compositions containing thiazolidinone derivatives |
| abstract |
The present invention relates to a method of screening for small organic molecules that directly inhibit the interaction of glycosaminoglycans (GAGs) with GAG-binding viral proteins (GBVPs), which comprises contacting a GAG with an GBVP in the presence of at least one candidate compound; and measuring the amount of the GAG bound to the GBVP or the amount of the GBVP bound to the GAG, wherein a significant decrease in GAG-GBVP binding as compared to GAG-GBVP binding in the absence of the candidate compound, identifies said compound as inhibitor of the GAG-GBVP interaction. The invention further provides pharmaceutical compositions comprising certain 2-thioxo-thiazolidinone derivatives, particularly useful against virus infections. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8933075-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109748910-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109748910-B |
| priorityDate |
2004-03-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |