| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cc2baff5061b50ba3dc6e9077ad27aba
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f27344b33f9ccd92e94776d9a8e12ad6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4c516d1dc461b170764edf50df80538f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_faa0630426f1744f298e3bceb1152864 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D413-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D271-07 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D271-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-41
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4245
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-44
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D271-10 |
| filingDate |
2005-03-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7744a430eed4d33001a4ed3b0650d490
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6b0ffe44326e7c6e41a87c3d3398819d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_82861e09b0c7b6b2ce73d4217dc24bd2 |
| publicationDate |
2005-11-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2005086871-A9 |
| titleOfInvention |
Compounds, compositions and methods for inhibiting or treating hiv-1 |
| abstract |
There is disclosed a structural genus of compounds, defined according to coordinates in three-dimensional space, that bind amino moieties on neighboring residues in a tyrosine residue 29 pocket of the matrix protein component of the HIV-1 preintegration complex (PIC), thereby preventing the PIC from binding to karyopherin a and preventing nuclear importation and integration of the HIV-1 viral genome into the host cell DNA, thereby preventing viral infection. The compounds may be utilized alone or in combinations with known inhibitors for preventing or inhibiting HIV-1 infection. |
| priorityDate |
2004-03-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |