| abstract |
The invention provides a 12kDa protein, herein designated muscle-relaxing protein (MRP), obtainable from the lysate or from the growth medium of Leishmania major organisms and capable of causing reversible muscle relaxation, and useful for treatment or prevention of a cardiac disease or condition such as angina pectoris, cardiac arrythmia, heart failure, or myocardial infarction, hypertension, a respiratory such as asthma, emphysema, pneumonia or bronchitis, and for the prevention of premature labor. |