Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_af059ebd4bc0e0b9dc86b3c842381297 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1c244b35e7797aaf333384ca98a75f98 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_33e0cb77260827966a920f9232dfb4f9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fdb6bc1924587c236d12fa451f9fb3c6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_95f94c840e245e733ff662f87ab1c108 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C45-292 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K51-0459 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4184 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D235-20 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F13-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4184 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K51-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K51-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D403-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D403-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D235-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K2-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61N5-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-31 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-02 |
filingDate |
2005-02-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7b3736f4c50ceb7286311615e73cc236 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_130eb8f8b19be3fec893f243d7e84bb3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_23a1ded44d0c20a47f36526f91bd8639 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_74365f265eb5dce2b9ad7f89ae4c2c00 |
publicationDate |
2005-09-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2005082894-A1 |
titleOfInvention |
Cell targeting conjugates |
abstract |
The present invention relates to cell targeting conjugates and in particular, but not exclusively, to methods of their use in selectively eliminating and in selectively imaging target cells. The invention also relates to processes for production of the conjugates and to intermediate compounds that may be used in production of a specific class of cell targeting conjugates. In one embodiment there is provided a cell targeting conjugate comprising the following components that are covalently conjugated via a linker that is degradable within the target cells: i) a DNA minor groove binding ligand incorporating an effective Auger electron-emitting and/or gamma-emitting and/or positron-emitting atom or photoactive moiety; ii) a target cell specific protein or peptide that is capable of internalisation by target cells. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10118920-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2013016321-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9056887-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021118927-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10428065-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103497224-A |
priorityDate |
2004-02-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |