| abstract |
À process for the preparation of optically active substituted alpha-indanyl amide derivatives of formula (I), which comprise*: - an asymmetric hydrogenation reaction of an en-amide derivative óf formula (III) in presence of hydrogen and an optically active catalyst, in order to obtain an amide derivative of formula (II), a hydrolysis reaction of the amide derivative of f ormula (II) obtained in the previous step, in order to obtain optically active substituted alphaindanyl amide derivatives of formula (I). Formula (I), Formula (II) and Formula (III). |