http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2005079817-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_773d3f5ebb1d3e074ebe28411f1fa61a http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1dd98ad4ee076841fec541542f952f58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1a1a86a59dcc45e4476632c50cea405a |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-727 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-727 |
| filingDate | 2005-02-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9366f791099072a21c43aa0a1c8fc2aa http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_86a57dc4fc8f64a2d8af2503639f1bc4 |
| publicationDate | 2005-09-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-2005079817-A1 |
| titleOfInvention | Affinity purified heparin/heparan sulfate for controlling the biological activity of the fgf receptor |
| abstract | Methods and compositions for modulating the activity of a FGF receptor in a mammal are disclosed. The methods and compositions utilize substantially purified heparin/heparan sulfate oligosaccharides (HS) that have high affinity for FGF7. HS that has high affinity for FGF7 has increased activity for promoting the formation of a ternary FGF/HS/FGFR complex. According to one embodiment of the invention, substantially purified HS is an octasaccharide having 7 or 8 sulfates and having predominant disaccharide composition of ΔHexA2SG1cN6S and a tri-sulfated disaccharide. Alternatively, the substantially purified HS is a longer oligosaccharide that contains an octasaccharide structural motif having 7 or 8 sulfates and having predominant disaccharide composition of ΔHexA2SG1cN6S and a tri-sulfated disaccharide. |
| priorityDate | 2004-02-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 49.