| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e2a6c5deed6e1eb98f905426ecba7a30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f132e4f2f62d40a9309ac2badcb8927d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ebb6a553affdc364c91cffe3baf12564 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4422
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-401 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-401
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-55
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4422 |
| filingDate |
2005-02-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cf4a4fb6ab08403fb722854e818ad297
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9f7491fb4c630130e21c3b7a1d40d1d6 |
| publicationDate |
2005-09-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2005079772-A2 |
| titleOfInvention |
Combination of (s)-amlodipine and an ace inhibitor, and methods for reducing hypertension |
| abstract |
The present invention generally relates to pharmaceutical compositions comprising optically pure (S)-amlodipine and an ACE inhibitor. In a preferred embodiment the (S)-amlodipine is (S)-amlodipine-L-malate, or a polymorph, pseudopolymorph or solvate thereof. In a preferred embodiment, the ACE inhibitor is ramipril. The pharmaceutical compositions of the invention are useful in the treatment of hypertension. The present invention also relates to a method of treating a patient suffering from hypertension or a cardiac disorder, comprising co-administering a therapeutically effective amount of optically pure (S)-amlodipine and an ACE inhibitor. In a preferred embodiment the (S)-amlodipine is (S)-amlodipine-L-malate, or a polymorph, pseudopolymorph or solvate thereof. In a preferred embodiment, the ACE inhibitor is ramipril. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102370965-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11701326-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2538924-A2 |
| priorityDate |
2004-02-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |