abstract |
The present invention relates to an extended release formulation that includes a drug capable of dissociating into a valproate ion, from about 15% to about 50% w/w of a high viscosity grade hydroxypropyl methylcellulose, and from about 0.1% w/w of a low viscosity grade hydroxypropyl methylcellulose. The drug capable of dissociating into a valproate ion may be valproic acid and its pharmaceutically acceptable salts, esters, and amides. |