| abstract |
The invention provides a human mGluR8 which is associated with the gastroenterological diseases, cancer, neurological diseases, urological diseases, respiratory diseases, cardiovascular diseases,. The invention also provides assays for the identification of compounds useful in the treatment or prevention of gastroenterological diseases, cancer, neurological diseases, urological diseases, respiratory diseases, cardiovascular diseases,. The invention also features compounds which bind to and/or activate or inhibit the activity of mGluR8 as well as pharmaceutical compositions comprising such compounds. |