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classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D333-16
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D333-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D333-16
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filingDate 2005-01-18-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_53707ec51ab9cb8e969ad8160886f810
publicationDate 2005-08-11-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-2005073215-A1
titleOfInvention Method for producing enantiomer-pure aminoalcohols
abstract The invention relates to a method for producing the enantiomer-pure aminoalcohol of formula (I), by (i) reducing the ketone of formula (3) to the racemic alcohol of formula (4), (ii) enantioselectively acylating the racemic alcohol of formula (4) with succinic anhydride in the presence of a lipase to the succinic acid semi-ester of formula (7), (iii) removing the succinic acid semi-ester of formula (7) from the unreacted enantiomer of formula (4), and (iv) reacting the enantiomer-pure alcohol of formula (4) with methylamine to give the enantiomer-pure alcohol of formula (1).
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priorityDate 2004-01-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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