Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5c94dcd338fd516ef7c00a780ebfb173 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0efa077d881a96aeb1e29b21ef1bbb58 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D333-16 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D333-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D333-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D333-14 |
filingDate |
2005-01-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_53707ec51ab9cb8e969ad8160886f810 |
publicationDate |
2005-08-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2005073215-A1 |
titleOfInvention |
Method for producing enantiomer-pure aminoalcohols |
abstract |
The invention relates to a method for producing the enantiomer-pure aminoalcohol of formula (I), by (i) reducing the ketone of formula (3) to the racemic alcohol of formula (4), (ii) enantioselectively acylating the racemic alcohol of formula (4) with succinic anhydride in the presence of a lipase to the succinic acid semi-ester of formula (7), (iii) removing the succinic acid semi-ester of formula (7) from the unreacted enantiomer of formula (4), and (iv) reacting the enantiomer-pure alcohol of formula (4) with methylamine to give the enantiomer-pure alcohol of formula (1). |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2643281-A4 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2643281-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8709751-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2008004191-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2011128370-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-101045936-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9758500-B2 |
priorityDate |
2004-01-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |