http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2005073209-A1

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assignee http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_54a074441d2d16a196cc9ef2c3b3f5bc
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_669b0dc0ff65a0d7f1fdc0a205183de7
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classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D305-14
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D305-14
filingDate 2005-01-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_67d04e1368dc9caa0126598c2d22cdc3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4d74b41a01b87600400748a2bc93e376
publicationDate 2005-08-11-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-2005073209-A1
titleOfInvention Method for the preparation of synthesized taxanoids
abstract This invention relates to the preparation process of synthesized taxanoids, including protection the 7-OH with rare earth elements compounds. In this process, the reactions are simple, and the binding is firm and reliable. And in the subsequent process, no acrylated 7-OH product will b~ produced, at the same time, it become readily controllable for the hydrolysis of 2- ester group of the acrylated product. In the preparation process of synthesized taxanoids of the present invention, THF is used as medium for the acrylation reaction, and can not only achieve the same effect as that of pyridine, but also avoid the unpleasant ordour, thus solve the problem of extremely high requirements for the field of production. The method of the present invention can be used not only for the preparation of semi-synthesized taxanes starting from natural taxanoids, but also for preparation of the total-synthesized taxanes.
priorityDate 2004-01-16-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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