| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b94d583f15f212baf5b917cbf8c18cdc
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_43a72884e25aaecffebe0942132d704f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fca4ca87e17f7bfe5e366c0b55eaae1e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_14a9750cf55ddc7769a19c96db7781ef
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_60867eeac051ca001adebb32120e016b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_58a04d6adac20b943edd638eca596ab6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ce56cfbdba6e788784e8217e1f2416bc |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-64
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-825
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K33-34
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K33-243
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K33-24 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-07
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-825
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K33-243
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K33-24 |
| filingDate |
2005-01-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_78d2186b0ed7e6e2be5219f5ee3c868f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4e21b1cc8c48b94e6ad376819b1a1c86
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3335b84f15a229988bf4d3b8355ce2d4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fddc88908e56d77af62660ece9d6985a |
| publicationDate |
2005-08-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2005072270-A2 |
| titleOfInvention |
Methods and compositons for treating cancer |
| abstract |
Pharmaceutical compositions, kits and methods useful for the treatment of cancer include a composition containing a modified metallothionein (MT) amino acid sequence or fragment thereof that binds the megalin receptor less avidly than naturally-occuring metallothionein. The modified metallothionein can be in a conjugate with multiple molecules of a therapeutic divalent metal ion. Embodiments of the modified metallothionein complex can bave a negative or neutral charge or a size greater than 70kD. Such compositions are useful also in methods for treating heavy metal poisoning and inhibiting renal uptake of therapeutic divalent metal ions. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8618060-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9518089-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10100100-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010166759-A1 |
| priorityDate |
2004-01-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |