| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3cd3ea6c52ef8544c67c051a2ef489b3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e7c70cd84ffc0e4ada7929a85622b4a0
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a392fd31ac958547aafaeac4b8ae9afb |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D263-58
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D263-58 |
| filingDate |
2005-01-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5ae26ad0f18557edcbca499b32dd6656
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3742667113974ca0b46942ae201f410d |
| publicationDate |
2005-08-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2005070907-A1 |
| titleOfInvention |
Cyclic diamine compound and pharmaceutical containing the same |
| abstract |
The present invention relates to 2-[4-[2-(7-trifluoromethylbenzoxazol-2-ylthio)ethyl]piperazin-1-yl]-N-[4-hydroxy-2,6-bis(trifluoromethyl)phenyl]acetamide or salt thereof, and an intermediate for the preparation thereof. The above-described compound has both an inhibitory action on ACAT in the artery wall and remarkably high meta-bolic resistance in human liver microsomes, and exhibits excellent effects for suppressing lipids depression in aorta in vivo so that it is useful as a highly effective preventive or remedy for hyperlipidemia and arteriosclero-sis with less side effects. |
| priorityDate |
2004-01-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |