http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2005068648-A1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_38c24fde5f99c1cdc06bf70936bd4a9d http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9059fb91e79718057a75e72ddc8847b3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6b2787fb8ac35a9508a61655fbcf73db http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ff3e741d8c3082a79ba472a5a4c2bef8 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6827 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
filingDate | 2005-01-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3ee8d7a82e281153972d360cc61d7b35 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_67c773d4b8b6bbdca71383213c3b5f79 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_36e7dc8bf02f1e3770d5b686041700c1 |
publicationDate | 2005-07-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | WO-2005068648-A1 |
titleOfInvention | Method for investigating cytosine methylation in dna by means of dna repair enzymes |
abstract | The following invention concerns a method for investigating cytosine methylation by means of DNA repair enzymes. Here, the DNA is first converted so that unmethylated cytosines are converted to uracil, while 5-methylcytosine remains unchanged. Then the DNA is hybridized to oligonucleotides, whereby hybrids will be formed with or without erroneous base pairings, in each case depending on the methylation status of the DNA. Following this, the erroneously paired hybrids will be cleaved by repair enzymes. Then the methylation status of the DNA can be determined in different ways. The method according to the invention is particularly suitable for the diagnosis and prognosis of cancer disorders and other diseases associated with a change of the methylation status as well as for predicting undesired drug effects. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2006009870-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2006009870-A2 |
priorityDate | 2004-01-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 223.