Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_54fed9961785bbf9faead9e2f46084c8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_69dd743ac109440df11e83e2ef8567e5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_28e3113097dd6d28720572e47f2f2407 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f7a22d554047937f316bc2c5d144efc1 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-044 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-92 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5038 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-92 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50 |
filingDate |
2004-12-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6886949eb49ce67c6ba0be3d3d4e24f4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b35da8794e825f808132a81a2e3a61f7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bda515c398807214674e8cdbc5ab2c34 |
publicationDate |
2005-07-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2005064344-A1 |
titleOfInvention |
Method of predicting abnormality of lipid metabolism |
abstract |
It is intended to provide a method of predicting abnormality of lipid metabolism caused by a compound characterized by comprising detecting, in a sample collected from a mammal with the administration of the compound or cultured mammalian tissue or cells exposed to the compound, (a) phenylacetylglycine and/or phenylacetylglutamine or an arbitrary metabolic intermediate in the metabolic pathway from phenylalanine into phenylacetylglycine or phenylacetylglutamine, and (b) hippuric acid or an arbitrary metabolic intermediate in the metabolic pathway from phenylalanine into hippuric acid, and using the quantitative ratio of them as an indication to thereby predict the possibility of the induction of abnormality of lipid metabolism by the compound. It is also intended to provide a method of diagnosing abnormality in lipid metabolism and related diseases characterized by comprising detecting the above-described (a) and (b) in a sample collected from a mammal and making a diagnosis with the use of the quantitative ratio of them as an indication. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2009502151-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2012179057-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2007315852-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2010506177-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2015129776-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2009145260-A |
priorityDate |
2003-12-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |