http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2005059100-A2
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fcf5f37c0d3d96c3d88447ca79082f12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ed28726de9f916f355f8adc331e736b8 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-57 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N- http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K17-00 |
filingDate | 2004-12-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_587c69d0cb83ff51c62615ab1d8faf08 |
publicationDate | 2005-06-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | WO-2005059100-A2 |
titleOfInvention | Methods and compositions relating to cystatin c |
abstract | A method of treating amyloidoses by administering an effective amount of a cystatin C composition or by increasing protein expression of cystatin C. A method of preventing fibril formation or deposition by administering an effective amount of a cystatin C composition or by binding amyloid proteins with an effective amount of a cystatin C composition. A composition for treating amyloidoses or for preventing fibril formation or deposition including an effective amount of a cystatin C composition. A method of preventing or treating hemorrhages by preventing or inhibiting local or systemic accumulation of cystatin C. A method of preventing or treating hemorrhages by preventing or inhibiting binding of cystatin C to specific blood vessel walls components, to cells that compose the blood vessel walls such as endothelial and smooth muscle cells, and to cell surface proteins associated with amyloid deposits. A method of preventing or treating hemorrhages by blocking or altering cell surface markers associated with cystatin C peptides, preventing or inhibiting binding of cystatin C to components of the blood such as proteins, lipids, or cells, and preventing inhibition of proteases in the circulation. A composition for preventing or treating hemorrhages including a peptide that competes with cystatin C binding with cell surface proteins associated with amyloid deposits. A marker for differentiating disease cases and controls, detecting very early stages of diseases such as AD. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102071214-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2094832-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8420613-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7790673-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8691519-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2094832-A4 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9347085-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2008060613-A1 |
priorityDate | 2003-12-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 685.