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publicationDate 2005-06-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-2005058825-A1
titleOfInvention Amlodipine gentisate and a method of its preparation
abstract The present invention relates to an acid salt of amlodipine gentisate and a method of its preparation. More particularly, the present invention relates to a crystalline acid salt of amlodipine gentisate of the following formula 1 prepared by reacting amlodipine and gentisic acid, which is useful for the treatment of cardiovascular diseases and has the advantages of low toxicity, excellent stability, improved pharmaceutical efficacies and long-lasting concentration in blood.
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