Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_938a6d7a15cbc93a74abe1953eb25d47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6af6e1e3cb8c9146195ea81ef451801b http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5a7c337699c78c120e00db0ae11623bc http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a9186e4bb8c26502fc9dee41b26ed067 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6924a637e3e62a6fc80a5da0dcb43a9d http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c370681a3db9fe245a91fbb0739fb417 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B15-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2299-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-1205 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B15-30 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G06F19-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G16B15-30 |
filingDate |
2004-12-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1b3ddb11d00a4a0294b5512d74826776 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b93dc08a6e00cdf455db23a0be768104 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3c8d50c149e559549bf6e08c02d0f627 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_584355cb37c1735856ef2090e822871a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_010ceedabf9cc9c110cb7f54ea34e14f |
publicationDate |
2005-06-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2005056785-A2 |
titleOfInvention |
Crystal structure of interleukin-2 tyrosine kinase (itk) and binding pockets thereof |
abstract |
The invention relates to molecules or molecular complexes which comprise binding pockets of ITK or its structural homologues. The invention relates to crystallizable compositions and crystals comprising ITK. The present invention also relates to a data storage medium encoded with the structural coordinates of molecules and molecular complexes which comprise the ITK or ITK-like ATP-binding pockets. The present invention also relates to a computer comprising such data storage material. The computer may generate a three-dimensional structure or graphical three-dimensional representation of such molecules or molecular complexes. This invention also relates to methods of using the structure coordinates to solve the structure of homologous proteins or protein complexes. In addition, this invention relates to methods of using the structure coordinates to screen for and design compounds, including inhibitory compounds, that bind to ITK or homologues thereof. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2019074275-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2020536093-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11149019-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2013153539-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2019013562-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11180496-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020045941-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021172922-A1 |
priorityDate |
2003-12-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |