| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_070a0598f9355667fdc2018f17fd5848
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3120ae9cab5bb4831f0cc16288966367
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5a1a9085fc6d1ba0f3ffbb41e30111b2
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_592d53a6d1a703280b6e91ff337fd1f7 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-14 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P13-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1138 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-39
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-113 |
| filingDate |
2004-12-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3ea947ffe54e6a725b89c17d59fcff4f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0dc7094d157d3a855824002e8649631b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_89d38b6fe1388aa50387b34da736a1d6 |
| publicationDate |
2005-06-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2005056598-A2 |
| titleOfInvention |
Laminin-5 modulators and uses thereof |
| abstract |
Described herein are methods of treating or preventing various diseases and disorders using modulators of laminin-5. Exemplary diseases and disorders are inflammatory bowel disease, including ulcerative colitis and Crohn's disease, as well as polycystic kidney disease and cancers associated with one or more of the aforementioned conditions. Exemplary laminin-5 modulators include monoclonal antibodies against the laminin-5 gamma2 chain and short interfering RNA (siRNA) sequences against nucleotide sequences encoding the laminin-5 gamma2 chain. Described are also combination treatments based on the administration of a laminin-5 modulator and at least one other therapeutic agent. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103149371-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110646624-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8545845-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2198884-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10716837-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8431686-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103149371-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2010070134-A1 |
| priorityDate |
2003-12-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |