| abstract |
Non-tabletted, individually dosed administration forms comprising a composition of at least one pharmaceutically active substance dissolved or dispersed within a matrix material comprising a mixture of at least 0,2% by weight of a gelatine, at least one stabilising agent and at least one water-soluble alcohol and/or water as a solvent, which composition is plastic at elevated temperature, characterised in that : the stabilising agent is selected from the group consisting of (i) esters of glycerine and fatty acids; (ii) products resulting from the alcoholysis / esterification reaction of such esters of glycerine and fatty acids with polyethylenglycols; and, in that the stabilising agent has a melting point in the range of 42° C to 63° C, in that water is present in an amount not greater than 46% by weight of the composition. |