Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_17b97eb5a76b3949f9c854477283b46c http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_44062378454230cde5788bd85a32fc3d http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_33b011e77b33662b8bf1f2ff2de7b661 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-1205 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-713 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4746 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4703 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-713 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-12 |
filingDate |
2004-05-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_66255ea14ef2e5907ac38e8da3e439b4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d53e24cc055d044147cc669f5cd4add8 |
publicationDate |
2005-05-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2005047504-A1 |
titleOfInvention |
Induction of cellular senescence by cdk4 disruption for tumor suppression and regression |
abstract |
The invention provides methods of inhibiting growth of tumor cells comprising contacting the cells with a Cdk4 inhibitor. The invention also provides methods of treating patients having, suspected of having, or at a high risk for developing, a cancer, comprising treatment with a Cdk4 inhibitor. The invention also relates to pharmaceutical compositions for treating such patients, wherein the pharmaceutical compositions comprise a Cdk4 inhibitor. The invention further relates to Cdk4 siRNA molecules capable of inhibiting Cdk4 expression or activity. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8389486-B2 |
priorityDate |
2003-11-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |