Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d98e48489d25e726d432addf0f5f76b4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_66c1b22707b0276e3078713a6ddcba91 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f074abc704606659ee445f37c71c27aa http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_16858e8eb37c33227ecf675002c0f9cf http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c485e6b575b141a77347283d1e33a365 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d202e9e866984fe229f6facc38f1d740 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_673d593b7606ece03af4f14c01dd0437 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1203c136551d1a7f32837f56ddab18b6 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2770-24221 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2770-24222 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-707 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N7-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-005 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N- http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-70 |
filingDate |
2004-11-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4301b594fb26b84b33b2943e8bb54aee http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_797b3de93122d001874148e1e6129303 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bd0ae9392bf2504c5b9d65e18eaa6cbf http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f549f4775b28187eca311bd760a70d97 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a2906b69f684f4716d7fe7eb3a216587 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_57a8c1a0e639fff9a549c7d2b8672cca |
publicationDate |
2005-05-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2005047463-A2 |
titleOfInvention |
Hcv replicons containing ns5b from genotype 2b |
abstract |
The present invention features methods for enhancing the ability of a genotype 2b NS5B sequence to function in a replicon, for producing replicons containing a functional genotype 2b NS5B, and for using replicons to measure the ability of a compound to affect HCV replication that is sustained with the genotype 2b polymerase. Also featured is a genotype 1b NS4B adaptive mutation. The ability to produce replicons containing a functional genotype 2b NS5B is illustrated by the production of chimeric replicons based on HCV genotype 1b where substantially all the NS5B sequence is replaced with a genotype 2b NS5B. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8618275-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8569472-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8772022-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8506969-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8945584-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8663653-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2008125119-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2008141651-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2008125117-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8454974-B2 |
priorityDate |
2003-11-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |