| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ceded95acb53d26c8ac4f0690e57d3d7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e0b6795732797acf34c0579ac71f2d2c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6e768b109c1f123b6ce3734db668b6be
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1721d75f5bf603447ec5a26b5c1c0be0
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5e73139532fc59f3862b11b47044d9fd
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5cac4532525846bde30d46be6a82b5bf |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D493-22 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D307-93
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D307-94
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01D-
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D307-77 |
| filingDate |
2004-11-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_aeeae4f76c1a2c62db1d044860107455
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_76ec5727752888cb94eabf9ada892e5f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f700e4255469f0285d39505a0239408d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fd1b3f2c0613214bbe3a019bad1c1624
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7d0a1c01181c9bb6322cc9a9acedb778 |
| publicationDate |
2005-12-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2005046829-B1 |
| titleOfInvention |
Separation of ginkgolides and bilobalide from g. biloba |
| abstract |
The subject invention provides a method for separating a terpene trilactone from Ginkgo biloba plant material or from an extract of Ginkgo biloba comprising a mixture of terpene trilactones, the process comprising the steps of: a) subjecting the Ginkgo biloba plant material or the extract to column chromatography with an appropriate solvent system to produce at least a first fraction containing the terpene trilactone bilobalide, a second fraction eluted after the first fraction containing the terpene trilactones GA and GB, and a third fraction eluted after the second fraction containing at least a preponderance of the terpene trilactones GC and GJ; and b) alkylating the terpene trilactone GB of the second fraction so as to produce a first mixture including terpene trilactone GA and alkylated terpene trilactone GB; or alkylating the terpene trilactone GC of the third fraction so as produce a second mixture including terpene trilactone GJ and alkylated terpene trilactone GC, so as to thereby isolate a terpene trilactone. |
| priorityDate |
2003-11-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |