| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b53290ef881bc16e92cfbaf0cd9605a7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_af5790bbb800ef658f64de9f0bd458d0
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cd2c3900689abdaedb13713965cfb0fa
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a77b8cc427db284b23b54636b37e89a0 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61F2002-91541
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61F2250-0068
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61F2210-0076
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2420-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-416
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2420-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-61
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-606
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-43 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L31-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L31-146
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L31-148
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L31-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L31-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61F2-91
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61F2-915 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61F2-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61F2-90
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L31-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L31-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L31-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61F2-06 |
| filingDate |
2004-11-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2aa907ceab40605bfb943c6afb2c3bb7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_71560233bc81d6b94771b84f6062a019
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3ac08699e20a3a8cbe4b5183e10e4494 |
| publicationDate |
2005-05-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2005046521-A1 |
| titleOfInvention |
Expandable medical device with beneficial agent matrix formed by a multi solvent system |
| abstract |
A multi solvent drug delivery matrix formation method is used to place layers into a reservoir in a stmt in a stepwise manner to achieve extended delivery of water soluble, sensitive, or difficult to deliver drugs. The multi solvent matrix formation method allows the formation of a drug reservoir with a layered morphology in which the mixing between layers is limited to allow the different layers to perform different functions in controlling drug delivery. A stmt having a drug delivery matrix includes a first beneficial agent layer affixed to the stmt by depositing a first solution of a first polymer and a first solvent, and a second beneficial agent layer affixed to the first beneficial agent layer by depositing a second solution of a second polymer and a second solvent. The second solvent is selected so that the first polymer is substantially insoluble in the second solvent to prevent degradation of the first polymer during deposition of the second polymer. A therapeutic agent is provided in the first beneficial agent layer or the second beneficial agent layer to form a drug delivery matrix. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10098989-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2111818-A4
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7658758-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9821091-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7758636-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9254202-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2111818-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8980323-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2006063430-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2007146049-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10744233-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7820193-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2007146049-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8349390-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2008026644-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7842083-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8449901-B2 |
| priorityDate |
2003-11-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |