| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7be4c1ec710a6f7449ead987c614367f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4c979ac4cb4175e79af937832ccbc141
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ee022227683d1f0128b9e194bc1990f9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2a320ad5d58d4d691f049d1d930ea9cd
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a3836552279da90283e9a94037b36b45 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-70575 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-705
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N- |
| filingDate |
2004-10-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_953127561cc486aa3c0f3e03a549ec31
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e7e1852adb144647d89597bc980debb3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_03183eeb3d63a65fbc5e312723465b7a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7792a6bdb94f84166fa9f11ad64b5b43
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8e69ba4c649b352e3b466dfd90fa864e |
| publicationDate |
2005-05-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2005040335-A2 |
| titleOfInvention |
A novel mutated nerve growth factor beta gene, proteins encoded thereby, and products and methods related thereto |
| abstract |
A point mutation responsible for loss of pain perception is identified and disclosed. The loss of pain perception resulting from the genetic mutation is characterized by impairment in the sensing of deep pain and temperature but with mental abilities and most other neurological responses intact. The mutation occurs in the coding region of the nerve growth-factor beta (NGFB). The NGF mutation separates the effect of NGF mediating a normal development of functions of the central nervous system, such as mental abilities, from effects on the nervous system involved in peripheral pain pathways. New screening methods, research tools, and therapies involving pain pathways related to the point mutation are provided. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112409471-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112409471-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2008006893-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114671940-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114671940-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114671942-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8487157-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2008106896-A1 |
| priorityDate |
2003-10-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |