Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8801aadfcf6361ade1cab718d90a17a0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b5e73495e43302ba9f5f5270549165c7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fc1a506cdfa120bc95f2833fd1d23421 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_250beb6ca22987484e9ccb0579b522bd |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-70589 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-755 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2035-124 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-71 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-70596 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-56966 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5005 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-569 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-12 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-569 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-02 |
filingDate |
2004-10-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_048038a0077ac34e1bc067e0939d4ee9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5fc7da8b5c57bb8861693adf1ff309ee http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a1db00db0c919e5f04efc4c62114140d |
publicationDate |
2005-04-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2005038454-A1 |
titleOfInvention |
In vitro method for the diagnosis of cardiovascular functionality of bone marrow precursor cells (bmp) and/or circulation precursor cells derived from blood (bdp) |
abstract |
The invention relates to an in vitro method for the analysis of a sample extracted from a mammal in relation to cardiovascular diseases. Said method comprises the following steps: a) the bone marrow precursor cells (BMP) and/or circulation precursor cells (BDP) derived from blood (BDP) are insulated by means of cell specific surface markers, and b) the cardiovascular functionality of the insulated BMP and/or BDP is examined by means of a suitable migration test. The inventive method can be used in the form of a kit in the field of diagnosis and/or prognosis of cardiovascular diseases, can be used to monitor the therapy thereof and/or for the stratification of cell therapy planted with stem cells and progenitor cells in order to increase perfusion of ischaemic tissue and/or for the regeneration of tissue loss (e.g. heart failure). The invention also relates to an in vitro method for the insulation of specific bone marrow precursor cells by means of a suitable migration test. Said BMP and/or BDP can be used in the treatment of cardiovascular diseases, selected from the group comprising stable coronary diseases, acute coronary syndrome, acute myocardial infarction, chronic ischaemic cardiomyopathy (ICMP), dilatative cardiomyopathy (DCM) or other causes of cardiac insufficiency. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8962320-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11714093-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105286819-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8315810-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2010135555-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8835384-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9765298-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2624498-C2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9932558-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8173118-B2 |
priorityDate |
2003-10-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |