| abstract |
This invention relates to a novel class of acidic amino acid/dicarboxylic acid derivatives (sulfonic acid/sulfate derivatives of naturally occurring amino acids and their amides) useful as inhibitors of osteoclastogenesis. The invention also provides methods of using the novel class of acidic amino acid/dicarboxylic acid derivatives of the general formula Z-OC-CRn1Rn2-COOZ, wherein n1=n2= 1 to 8 and Z=OH or NH2 and its derivatives for inhibition of osteoclastogenesis. |